Gene description for Xylt2
Gene name xylosyltransferase II
Gene symbol Xylt2
Other names/aliases E030002B02Rik
XT-II
XT2
xylT-II
Species Mus musculus
 Database cross references - Xylt2
ExoCarta ExoCarta_217119
Vesiclepedia VP_217119
Entrez Gene 217119
UniProt Q9EPL0  
 Xylt2 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Xylt2
Molecular Function
    magnesium ion binding GO:0000287 ISO
    magnesium ion binding GO:0000287 ISS
    manganese ion binding GO:0030145 ISO
    manganese ion binding GO:0030145 ISS
    protein xylosyltransferase activity GO:0030158 IBA
    protein xylosyltransferase activity GO:0030158 IDA
    protein xylosyltransferase activity GO:0030158 IMP
    protein xylosyltransferase activity GO:0030158 ISO
    protein xylosyltransferase activity GO:0030158 ISS
Biological Process
    glycosaminoglycan biosynthetic process GO:0006024 IMP
    glycosaminoglycan biosynthetic process GO:0006024 IMP
    heparan sulfate proteoglycan biosynthetic process GO:0015012 IBA
    heparan sulfate proteoglycan biosynthetic process GO:0015012 IEA
    heparan sulfate proteoglycan biosynthetic process GO:0015012 ISO
    heparan sulfate proteoglycan biosynthetic process GO:0015012 ISS
    proteoglycan biosynthetic process GO:0030166 IMP
    chondroitin sulfate biosynthetic process GO:0030206 IEA
    heparin biosynthetic process GO:0030210 IMP
    chondroitin sulfate proteoglycan biosynthetic process GO:0050650 IBA
    chondroitin sulfate proteoglycan biosynthetic process GO:0050650 ISO
    chondroitin sulfate proteoglycan biosynthetic process GO:0050650 ISS
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    extracellular space GO:0005615 ISO
    extracellular space GO:0005615 ISS
    Golgi apparatus GO:0005794 ISO
 Experiment description of studies that identified Xylt2 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Xylt2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Xylt1 233781
Co-fractionation Mus musculus
View the network image/svg+xml



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