Gene description for Trf
Gene name	transferrin
Gene symbol	Trf
Other names/aliases	AI266983 Cd176 HP Tf Tfn hpx
Species	Mus musculus
Database cross references - Trf
ExoCarta	ExoCarta_22041
Entrez Gene	22041
UniProt	Q921I1
Trf identified in exosomes derived from the following tissue/cell type
Brain cancer cells	19109410
Mast cells	17486113

Gene ontology annotations for Trf

Molecular Function     ferric iron binding GO:0008199 ISO     ferric iron transmembrane transporter activity GO:0015091 ISO     metal ion binding GO:0046872 IEA     protein binding GO:0005515 IPI Biological Process     positive regulation of oligodendrocyte progenitor proliferation GO:0070447 ISO     ion transport GO:0006811 IEA     positive regulation of phosphorylation GO:0042327 IDA     transport GO:0006810 IEA     osteoclast differentiation GO:0030316 IDA     positive regulation of transcription, DNA-templated GO:0045893 IDA     positive regulation of bone resorption GO:0045780 IDA     iron ion homeostasis GO:0055072 IEA     ERK1 and ERK2 cascade GO:0070371 IDA     iron ion transport GO:0006826 IMP     ferric iron transport GO:0015682 ISO     iron ion transmembrane transport GO:0034755 ISO     positive regulation of myelination GO:0031643 ISO     positive regulation of cell motility GO:2000147 IDA     activation of JUN kinase activity GO:0007257 IDA     actin filament organization GO:0007015 IDA     SMAD protein signal transduction GO:0060395 IDA     cellular iron ion homeostasis GO:0006879 IEA Subcellular Localization     early endosome GO:0005769 ISO     coated pit GO:0005905 ISO     extracellular exosome GO:0070062 ISO     dense body GO:0097433 ISO     extracellular space GO:0005615 ISO     late endosome GO:0005770 ISO     basal plasma membrane GO:0009925 ISO     apical plasma membrane GO:0016324 ISO     vesicle coat GO:0030120 ISO     endocytic vesicle GO:0030139 ISO     cell surface GO:0009986 ISO     vesicle GO:0031982 ISO     basement membrane GO:0005604 ISO     blood microparticle GO:0072562 ISO     membrane GO:0016020 IMP     endosome GO:0005768 IDA     cytoplasmic membrane-bounded vesicle GO:0016023 ISO     basal part of cell GO:0045178 ISO     perinuclear region of cytoplasm GO:0048471 ISO     extracellular region GO:0005576 IEA     recycling endosome GO:0055037 ISO