Gene description for Ugdh
Gene name UDP-glucose dehydrogenase
Gene symbol Ugdh
Other names/aliases Udpgdh
Species Mus musculus
 Database cross references - Ugdh
ExoCarta ExoCarta_22235
Entrez Gene 22235
UniProt O70475  
 Ugdh identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Ugdh
Molecular Function
    oxidoreductase activity GO:0016491 IEA
    NAD binding GO:0051287 IEA
    catalytic activity GO:0003824 IEA
    UDP-glucose 6-dehydrogenase activity GO:0003979 ISO
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 IEA
Biological Process
    metabolic process GO:0008152 IEA
    gastrulation with mouth forming second GO:0001702 IMP
    oxidation-reduction process GO:0055114 ISO
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Ugdh in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ugdh
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ugdh is involved
Formation of the active cofactor, UDP-glucuronate IEA Reactome

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