Gene description for Ncapd2
Gene name non-SMC condensin I complex, subunit D2
Gene symbol Ncapd2
Other names/aliases 2810406C15Rik
2810465G24Rik
CAP-D2
CNAP1
mKIAA0159
Species Mus musculus
 Database cross references - Ncapd2
ExoCarta ExoCarta_68298
Vesiclepedia VP_68298
Entrez Gene 68298
UniProt Q8K2Z4  
 Ncapd2 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ncapd2
Molecular Function
    histone binding GO:0042393 ISO
Biological Process
    cell cycle GO:0007049 IEA
    mitotic nuclear division GO:0007067 IEA
    cell division GO:0051301 IEA
    chromosome condensation GO:0030261 IEA
    mitotic chromosome condensation GO:0007076 ISO
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    chromosome GO:0005694 IEA
    nucleus GO:0005634 IEA
    nuclear chromosome GO:0000228 ISO
    cytoplasm GO:0005737 ISO
    membrane GO:0016020 ISO
    condensin complex GO:0000796 ISO
    pronucleus GO:0045120 IDA
    condensed chromosome GO:0000793 ISO
 Experiment description of studies that identified Ncapd2 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ncapd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ncapd2 is involved
PathwayEvidenceSource
Condensation of Prometaphase Chromosomes IEA Reactome





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