Gene description for Tomm22
Gene name translocase of outer mitochondrial membrane 22 homolog (yeast)
Gene symbol Tomm22
Other names/aliases 2310047D01
Tom22
Species Mus musculus
 Database cross references - Tomm22
ExoCarta ExoCarta_223696
Entrez Gene 223696
UniProt Q9CPQ3  
 Tomm22 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Tomm22
Molecular Function
    protein binding GO:0005515 IPI
    protein transmembrane transporter activity GO:0008320 ISO
Biological Process
    intracellular protein transport GO:0006886 IEA
    protein import into mitochondrial outer membrane GO:0045040 ISO
    transport GO:0006810 IEA
    protein transport GO:0015031 IEA
Subcellular Localization
    mitochondrial outer membrane GO:0005741 IEA
    membrane GO:0016020 ISO
    mitochondrion GO:0005739 ISO
    integral component of membrane GO:0016021 ISO
    mitochondrial outer membrane translocase complex GO:0005742 ISO
    mitochondrial inner membrane GO:0005743 IDA
 Experiment description of studies that identified Tomm22 in exosomes
1
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tomm22
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tomm22 is involved
PathwayEvidenceSource
Mitochondrial protein import IEA Reactome





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