Gene description for Tomm22
Gene name translocase of outer mitochondrial membrane 22 homolog (yeast)
Gene symbol Tomm22
Other names/aliases 2310047D01
Tom22
Species Mus musculus
 Database cross references - Tomm22
ExoCarta ExoCarta_223696
Entrez Gene 223696
UniProt Q9CPQ3  
 Tomm22 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Tomm22
Molecular Function
    protein binding GO:0005515 IPI
    protein transmembrane transporter activity GO:0008320 ISO
Biological Process
    intracellular protein transport GO:0006886 IEA
    protein import into mitochondrial outer membrane GO:0045040 ISO
    transport GO:0006810 IEA
    protein transport GO:0015031 IEA
Subcellular Localization
    mitochondrial outer membrane GO:0005741 IEA
    membrane GO:0016020 ISO
    mitochondrion GO:0005739 ISO
    integral component of membrane GO:0016021 ISO
    mitochondrial outer membrane translocase complex GO:0005742 ISO
    mitochondrial inner membrane GO:0005743 IDA
 Experiment description of studies that identified Tomm22 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tomm22
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tomm22 is involved
PathwayEvidenceSource
Mitochondrial protein import IEA Reactome





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