Gene description for Baz1b
Gene name bromodomain adjacent to zinc finger domain, 1B
Gene symbol Baz1b
Other names/aliases C87820
WSTF
Wbscr9
Species Mus musculus
 Database cross references - Baz1b
ExoCarta ExoCarta_22385
Vesiclepedia VP_22385
Entrez Gene 22385
UniProt Q9Z277  
 Baz1b identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Baz1b
Molecular Function
    vitamin D receptor activator activity GO:0071884 IMP
    transferase activity GO:0016740 IEA
    chromatin binding GO:0003682 ISO
    zinc ion binding GO:0008270 IEA
    protein binding GO:0005515 IPI
    nucleotide binding GO:0000166 IEA
    metal ion binding GO:0046872 IEA
    ATP binding GO:0005524 IEA
    lysine-acetylated histone binding GO:0070577 ISO
    histone kinase activity GO:0035173 ISO
    non-membrane spanning protein tyrosine kinase activity GO:0004715 IEA
    protein tyrosine kinase activity GO:0004713 ISO
    kinase activity GO:0016301 IEA
    histone binding GO:0042393 IPI
Biological Process
    chromatin assembly or disassembly GO:0006333 IDA
    cellular response to DNA damage stimulus GO:0006974 ISO
    chromatin-mediated maintenance of transcription GO:0048096 IMP
    positive regulation of receptor activity GO:2000273 IMP
    phosphorylation GO:0016310 IEA
    histone phosphorylation GO:0016572 ISO
    double-strand break repair GO:0006302 IMP
    transcription, DNA-templated GO:0006351 IEA
    chromatin remodeling GO:0006338 IDA
    regulation of transcription, DNA-templated GO:0006355 IMP
    heart morphogenesis GO:0003007 IMP
    peptidyl-tyrosine phosphorylation GO:0018108 ISO
Subcellular Localization
    condensed chromosome GO:0000793 IDA
    nuclear replication fork GO:0043596 ISO
    pericentric heterochromatin GO:0005721 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified Baz1b in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Baz1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Smarca5 93762
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
View the network image/svg+xml
 Pathways in which Baz1b is involved
No pathways found





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