Gene description for Lppr4
Gene name lipid phosphate phosphatase-related protein type 4
Gene symbol Lppr4
Other names/aliases A330086D10
D3Bwg0562e
PRG-1
mKIAA0455
Species Mus musculus
 Database cross references - Lppr4
ExoCarta ExoCarta_229791
Entrez Gene 229791
UniProt Q7TME0  
 Lppr4 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Lppr4
Molecular Function
    catalytic activity GO:0003824 IEA
    lipid phosphatase activity GO:0042577 ISO
    phosphatidate phosphatase activity GO:0008195 IEA
    protein binding GO:0005515 IPI
    hydrolase activity GO:0016787 IEA
Biological Process
    axonogenesis GO:0007409 ISO
    inner ear development GO:0048839 IDA
    phospholipid dephosphorylation GO:0046839 ISO
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    external side of plasma membrane GO:0009897 ISO
    integral component of plasma membrane GO:0005887 ISO
    membrane GO:0016020 IEA
 Experiment description of studies that identified Lppr4 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Lppr4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lppr4 is involved
No pathways found





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