Gene description for Fbxo44
Gene name F-box protein 44
Gene symbol Fbxo44
Other names/aliases 5730411K09
AV001623
FBG3
FBX30
Fbx6a
Fbxo6a
Species Mus musculus
 Database cross references - Fbxo44
ExoCarta ExoCarta_230903
Vesiclepedia VP_230903
Entrez Gene 230903
UniProt Q8BK26  
 Fbxo44 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Fbxo44
Molecular Function
    protein binding GO:0005515 IPI
    ubiquitin protein ligase activity GO:0061630 IBA
Biological Process
    glycoprotein catabolic process GO:0006516 IBA
    proteasomal protein catabolic process GO:0010498 ISO
    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031146 IBA
    ERAD pathway GO:0036503 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IEA
    SCF ubiquitin ligase complex GO:0019005 IBA
    SCF ubiquitin ligase complex GO:0019005 ISO
    SCF ubiquitin ligase complex GO:0019005 ISS
 Experiment description of studies that identified Fbxo44 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Fbxo44
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Skp1a 21402
Co-fractionation Mus musculus
2 Cul1 26965
Co-fractionation Mus musculus
View the network image/svg+xml



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