Gene description for FOXO3B
Gene name forkhead box O3B pseudogene
Gene symbol FOXO3B
Other names/aliases FKHRL1P1
ZNF286C
Species Homo sapiens
 Database cross references - FOXO3B
ExoCarta ExoCarta_2310
Vesiclepedia VP_2310
Entrez Gene 2310
HGNC 3822
 FOXO3B identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for FOXO3B
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    mitochondrial matrix GO:0005759 IBA
    cytosol GO:0005829 IEA
 Experiment description of studies that identified FOXO3B in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for FOXO3B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FOXO1  
Affinity Capture-MS Homo sapiens
2 FOXO3  
Affinity Capture-MS Homo sapiens
3 FOXN3 1112
Affinity Capture-MS Homo sapiens
4 FOXO6  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FOXO3B is involved
No pathways found





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