Gene description for Rbm10
Gene name RNA binding motif protein 10
Gene symbol Rbm10
Other names/aliases E430039K10Rik
Species Mus musculus
 Database cross references - Rbm10
ExoCarta ExoCarta_236732
Entrez Gene 236732
UniProt Q99KG3  
 Rbm10 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rbm10
Molecular Function
    nucleotide binding GO:0000166 IEA
    protein complex binding GO:0032403 ISO
    RNA binding GO:0003723 IEA
    identical protein binding GO:0042802 ISO
    zinc ion binding GO:0008270 IEA
    poly(A) RNA binding GO:0044822 ISO
    nucleic acid binding GO:0003676 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    positive regulation of smooth muscle cell apoptotic process GO:0034393 IDA
    negative regulation of cell proliferation GO:0008285 IGI
    3'-UTR-mediated mRNA stabilization GO:0070935 IDA
    negative regulation of mRNA splicing, via spliceosome GO:0048025 IMP
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA
    regulation of smooth muscle cell apoptotic process GO:0034391 IGI
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Rbm10 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rbm10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rbm10 is involved
No pathways found





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