Gene description for Zfp462
Gene name zinc finger protein 462
Gene symbol Zfp462
Other names/aliases 6030417H05
9430078C22Rik
Gt4-2
Zfpip
Species Mus musculus
 Database cross references - Zfp462
ExoCarta ExoCarta_242466
Entrez Gene 242466
 Zfp462 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Zfp462
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    negative regulation of DNA binding GO:0043392 IDA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA
    chromatin organization GO:0006325 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
 Experiment description of studies that identified Zfp462 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Zfp462
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Zfp462 is involved
No pathways found





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