Experiment description of studies that identified Cbx3 in sEVs

1 Experiment ID 907 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample Colon cancer cells Sample name C26 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 15 MISEV standards ✔ EM Biophysical techniques ✔ CD63 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule mrna Identification method Microarray PubMed ID 17486113     Organism Mus musculus Homo sapiens Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO" Journal name NCB Publication year 2007 Sample Mast cells Sample name MC9 Bone marrow-derived mast cells HMC-1 Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.11-1.21 g/mL Molecules identified in the study Protein mRNA miRNA Methods used in the study Mass spectrometry [MALDI TOF] Western blotting Microarray miRCURY LNA Array

3 Experiment ID 908 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample T-cell lymphoma cells Sample name EL4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for Cbx3

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Vezf1   Affinity Capture-MS Mus musculus 2 Prdm10   Affinity Capture-MS Mus musculus 3 Nphs2   Affinity Capture-MS Mus musculus 4 Cbx1   Affinity Capture-MS Mus musculus 5 Wiz   Affinity Capture-MS Mus musculus 6 HDAC4   Reconstituted Complex Homo sapiens 7 Zmym3   Affinity Capture-MS Mus musculus 8 Lmna 16905 Affinity Capture-MS Mus musculus 9 Trim28 21849 Affinity Capture-Western Mus musculus Affinity Capture-Western Mus musculus FRET Mus musculus Biochemical Activity Mus musculus Affinity Capture-Western Mus musculus Two-hybrid Mus musculus Affinity Capture-Western Mus musculus Reconstituted Complex Mus musculus Affinity Capture-MS Mus musculus 10 Zfp280c   Affinity Capture-MS Mus musculus 11 Mga   Affinity Capture-MS Mus musculus 12 Lrif1   Affinity Capture-MS Mus musculus 13 Tubb5 22154 Affinity Capture-MS Mus musculus 14 Adnp   Affinity Capture-MS Mus musculus Affinity Capture-MS Mus musculus Co-localization Mus musculus 15 Vim 22352 Affinity Capture-MS Mus musculus 16 Hist1h1e 50709 Affinity Capture-Western Mus musculus Reconstituted Complex Mus musculus Protein-peptide Mus musculus 17 Erh   Affinity Capture-MS Mus musculus 18 Kdm2b   Affinity Capture-MS Mus musculus Affinity Capture-Western Mus musculus 19 Tfe3   Affinity Capture-MS Mus musculus 20 Chd4 107932 Affinity Capture-MS Mus musculus 21 Hist1h2bb 319178 Affinity Capture-MS Mus musculus 22 Hnrnpa1 15382 Affinity Capture-MS Mus musculus 23 Ahdc1   Affinity Capture-MS Mus musculus 24 Fmr1   Affinity Capture-MS Mus musculus 25 Trim24   Biochemical Activity Mus musculus Reconstituted Complex Mus musculus 26 Tuba1b 22143 Affinity Capture-MS Mus musculus 27 Hist3   Protein-peptide Mus musculus 28 Runx1 12394 Affinity Capture-MS Mus musculus 29 Ehmt1   Affinity Capture-MS Mus musculus 30 H3f3a 15078 Protein-peptide Mus musculus 31 Hnrnpu 51810 Affinity Capture-MS Mus musculus 32 Rpl24 68193 Affinity Capture-MS Mus musculus 33 Pcgf6   Affinity Capture-MS Mus musculus 34 Zfp462 242466 Affinity Capture-MS Mus musculus 35 Chaf1a   Affinity Capture-MS Mus musculus 36 Rps11 27207 Affinity Capture-MS Mus musculus 37 Rps24 20088 Affinity Capture-MS Mus musculus 38 Mecp2   Affinity Capture-MS Mus musculus 39 Glyr1   Affinity Capture-MS Mus musculus 40 Hist1h3d 319149 Affinity Capture-MS Mus musculus 41 Ehmt2   Affinity Capture-MS Mus musculus 42 Rpl17 319195 Affinity Capture-MS Mus musculus 43 Max   Affinity Capture-MS Mus musculus 44 Mettl21e   Affinity Capture-MS Mus musculus 45 HDAC1 3065 Reconstituted Complex Homo sapiens 46 Zmym2   Affinity Capture-MS Mus musculus 47 Pogz   Affinity Capture-MS Mus musculus 48 Zfp280d 235469 Affinity Capture-MS Mus musculus 49 Rlf   Affinity Capture-MS Mus musculus 50 Cbx5   Affinity Capture-MS Mus musculus Affinity Capture-MS Mus musculus 51 Zmym4   Affinity Capture-MS Mus musculus 52 Slc25a5 11740 Affinity Capture-MS Mus musculus 53 Champ1   Affinity Capture-MS Mus musculus 54 Ran 19384 Affinity Capture-MS Mus musculus 55 Unk   Affinity Capture-RNA Mus musculus 56 Zfp518b   Affinity Capture-MS Mus musculus 57 Nanog   Affinity Capture-MS Mus musculus 58 H2-Ke6   Affinity Capture-MS Mus musculus 59 2410141K09Rik   Affinity Capture-MS Mus musculus 60 Zfp518a   Affinity Capture-MS Mus musculus 61 Rnf2   Affinity Capture-MS Mus musculus Affinity Capture-Western Mus musculus 62 Zbtb7b   Affinity Capture-MS Mus musculus 63 Suv39h1   FRET Mus musculus Affinity Capture-Western Mus musculus Affinity Capture-MS Mus musculus 64 Bahd1   Co-localization Mus musculus 65 Hnrnpf 98758 Affinity Capture-MS Mus musculus 66 Hspa8 15481 Affinity Capture-MS Mus musculus 67 Trim66   Two-hybrid Mus musculus Reconstituted Complex Mus musculus Affinity Capture-Western Mus musculus 68 Eed   Affinity Capture-MS Mus musculus 69 Mis18bp1   Affinity Capture-MS Mus musculus 70 Sirt1   Affinity Capture-Western Mus musculus 71 Zfp292   Affinity Capture-MS Mus musculus 72 Rpl10 110954 Affinity Capture-MS Mus musculus 73 Atg16l1   Affinity Capture-MS Mus musculus 74 HDAC5 10014 Reconstituted Complex Homo sapiens 75 L3mbtl2   Affinity Capture-MS Mus musculus 76 Tfdp1   Affinity Capture-MS Mus musculus 77 E2f6   Affinity Capture-MS Mus musculus 78 Fancd2   Affinity Capture-MS Mus musculus 79 Adnp2   Affinity Capture-MS Mus musculus 80 Hdac9   Reconstituted Complex Mus musculus View the network

Pathways in which Cbx3 is involved

No pathways found