Gene description for Shank1
Gene name	SH3/ankyrin domain gene 1
Gene symbol	Shank1
Other names/aliases	-
Species	Mus musculus
Database cross references - Shank1
ExoCarta	ExoCarta_243961
Vesiclepedia	VP_243961
Entrez Gene	243961
UniProt	D3YZU1
Shank1 identified in sEVs derived from the following tissue/cell type
Pancreatic cells	19351151

Gene ontology annotations for Shank1

Molecular Function     G protein-coupled receptor binding GO:0001664 ISO     protein binding GO:0005515 IPI     protein binding GO:0005515 ISS     SH3 domain binding GO:0017124 ISO     SH3 domain binding GO:0017124 ISS     signaling receptor complex adaptor activity GO:0030159 ISO     synaptic receptor adaptor activity GO:0030160 IBA     synaptic receptor adaptor activity GO:0030160 IMP     synaptic receptor adaptor activity GO:0030160 ISO     somatostatin receptor binding GO:0031877 ISO     somatostatin receptor binding GO:0031877 ISS     ionotropic glutamate receptor binding GO:0035255 IBA     ionotropic glutamate receptor binding GO:0035255 IPI     ionotropic glutamate receptor binding GO:0035255 ISO     identical protein binding GO:0042802 ISO     identical protein binding GO:0042802 ISS     protein-containing complex binding GO:0044877 ISO     protein-containing complex binding GO:0044877 ISS     ankyrin repeat binding GO:0071532 ISO     ankyrin repeat binding GO:0071532 ISS     scaffold protein binding GO:0097110 ISO     scaffold protein binding GO:0097110 ISS     structural constituent of postsynaptic density GO:0098919 IDA     structural constituent of postsynaptic density GO:0098919 IEP     structural constituent of postsynaptic density GO:0098919 IMP Biological Process     long-term memory GO:0007616 IMP     associative learning GO:0008306 IMP     adult behavior GO:0030534 IEA     adult behavior GO:0030534 ISO     negative regulation of actin filament bundle assembly GO:0032232 IDA     social behavior GO:0035176 IMP     social behavior GO:0035176 ISO     protein localization to synapse GO:0035418 IMP     olfactory behavior GO:0042048 IMP     habituation GO:0046959 IMP     modulation of chemical synaptic transmission GO:0050804 IDA     modulation of chemical synaptic transmission GO:0050804 IEP     modulation of chemical synaptic transmission GO:0050804 IMP     neuromuscular process controlling balance GO:0050885 IMP     determination of affect GO:0050894 IEA     determination of affect GO:0050894 ISO     righting reflex GO:0060013 IMP     synapse maturation GO:0060074 ISO     synapse maturation GO:0060074 ISS     dendritic spine morphogenesis GO:0060997 IMP     positive regulation of dendritic spine development GO:0060999 ISO     positive regulation of dendritic spine development GO:0060999 ISS     protein-containing complex assembly GO:0065003 ISO     protein-containing complex assembly GO:0065003 ISS     vocalization behavior GO:0071625 IMP     vocalization behavior GO:0071625 ISO     maintenance of postsynaptic density structure GO:0099562 IEA     regulation of AMPA receptor activity GO:2000311 IMP     positive regulation of excitatory postsynaptic potential GO:2000463 IMP Subcellular Localization     cytoplasm GO:0005737 IEA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     postsynaptic density GO:0014069 IBA     postsynaptic density GO:0014069 IDA     postsynaptic density GO:0014069 IDA     postsynaptic density GO:0014069 ISO     postsynaptic density GO:0014069 ISS     membrane GO:0016020 ISO     dendrite GO:0030425 IDA     neuron projection GO:0043005 IDA     dendritic spine GO:0043197 IBA     dendritic spine GO:0043197 IDA     dendritic spine GO:0043197 ISO     synapse GO:0045202 ISO     postsynaptic membrane GO:0045211 IBA     postsynaptic membrane GO:0045211 IDA     postsynaptic membrane GO:0045211 IDA     postsynaptic membrane GO:0045211 ISO     excitatory synapse GO:0060076 IDA     Schaffer collateral - CA1 synapse GO:0098685 IDA     Schaffer collateral - CA1 synapse GO:0098685 IEP     Schaffer collateral - CA1 synapse GO:0098685 IMP     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IEP     glutamatergic synapse GO:0098978 IMP