Gene description for Glud1
Gene name glutamate dehydrogenase 1
Gene symbol Glud1
Other names/aliases Ac2-281
Gdh1
Glud
Gludeha
MRG-2
Species Rattus norvegicus
 Database cross references - Glud1
ExoCarta ExoCarta_24399
Entrez Gene 24399
UniProt P10860  
 Glud1 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Glud1
Molecular Function
    enzyme binding GO:0019899 IPI
    ATP binding GO:0005524 IEA
    glutamate dehydrogenase [NAD(P)+] activity GO:0004353 ISS
    GTP binding GO:0005525 ISO
    glutamate dehydrogenase (NAD+) activity GO:0004352 ISO
    leucine binding GO:0070728 ISO
    ADP binding GO:0043531 ISO
    NAD+ binding GO:0070403 ISO
Biological Process
    glutamate biosynthetic process GO:0006537 ISO
    long-term memory GO:0007616 IEP
    response to aluminum ion GO:0010044 IDA
    oxidation-reduction process GO:0055114 ISO
    glutamate catabolic process GO:0006538 TAS
    tricarboxylic acid metabolic process GO:0072350 ISS
    positive regulation of insulin secretion GO:0032024 ISO
    substantia nigra development GO:0021762 ISO
    glutamine metabolic process GO:0006541 ISS
Subcellular Localization
    mitochondrial inner membrane GO:0005743 ISO
    mitochondrion GO:0005739 ISO
    mitochondrial matrix GO:0005759 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Glud1 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Glud1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DYNLL1 8655
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Glud1 is involved
PathwayEvidenceSource
Amino acid synthesis and interconversion (transamination) IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here