Gene description for Nars2
Gene name asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
Gene symbol Nars2
Other names/aliases AI875199
Species Mus musculus
 Database cross references - Nars2
ExoCarta ExoCarta_244141
Entrez Gene 244141
UniProt Q8BGV0  
 Nars2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nars2
Molecular Function
    aminoacyl-tRNA ligase activity GO:0004812 IEA
    asparagine-tRNA ligase activity GO:0004816 IEA
    ATP binding GO:0005524 IEA
    ligase activity GO:0016874 IEA
    nucleic acid binding GO:0003676 IEA
    nucleotide binding GO:0000166 IEA
Biological Process
    asparaginyl-tRNA aminoacylation GO:0006421 IEA
    translation GO:0006412 IEA
    tRNA aminoacylation for protein translation GO:0006418 IEA
Subcellular Localization
    mitochondrion GO:0005739 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Nars2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nars2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nars2 is involved
No pathways found





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