Gene description for Gstm1
Gene name glutathione S-transferase mu 1
Gene symbol Gstm1
Other names/aliases GSTA3
Species Rattus norvegicus
 Database cross references - Gstm1
ExoCarta ExoCarta_24423
Entrez Gene 24423
UniProt P04905  
 Gstm1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Gstm1
Molecular Function
    nickel cation binding GO:0016151 IDA
    glutathione transferase activity GO:0004364 ISO
    steroid binding GO:0005496 IPI
    enzyme binding GO:0019899 ISO
    protein heterodimerization activity GO:0046982 ISO
    glutathione binding GO:0043295 ISO
    protein homodimerization activity GO:0042803 ISO
Biological Process
    glutathione metabolic process GO:0006749 ISO
    cellular detoxification of nitrogen compound GO:0070458 ISO
    response to ethanol GO:0045471 IEP
    response to axon injury GO:0048678 IEP
    response to drug GO:0042493 IEP
    response to lithium ion GO:0010226 IEP
    response to metal ion GO:0010038 IEP
    response to antibiotic GO:0046677 IEP
    response to lead ion GO:0010288 IEP
    xenobiotic catabolic process GO:0042178 ISO
    sensory perception of smell GO:0007608 IEA
    nitrobenzene metabolic process GO:0018916 ISO
    response to amino acid GO:0043200 IEP
    cellular response to drug GO:0035690 ISO
    metabolic process GO:0008152 IEA
Subcellular Localization
    extracellular region GO:0005576 IDA
    protein complex GO:0043234 IDA
    myelin sheath GO:0043209 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Gstm1 in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Gstm1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gstm1 is involved
No pathways found





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