Gene description for Ppp2ca
Gene name	protein phosphatase 2, catalytic subunit, alpha isozyme
Gene symbol	Ppp2ca
Other names/aliases	Pp2a1
Species	Rattus norvegicus
Database cross references - Ppp2ca
ExoCarta	ExoCarta_24672
Entrez Gene	24672
UniProt	P63331
Ppp2ca identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Ppp2ca

Molecular Function     tau protein binding GO:0048156 IPI     protein phosphatase 2A binding GO:0051721 IPI     metal ion binding GO:0046872 IEA     enzyme binding GO:0019899 IPI     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 IPI     protein dimerization activity GO:0046983 IMP     protein phosphatase binding GO:0019903 IPI     protein complex binding GO:0032403 IPI     protein domain specific binding GO:0019904 IDA     protein antigen binding GO:1990405 IPI     GABA receptor binding GO:0050811 ISO     protein heterodimerization activity GO:0046982 ISS     protein serine/threonine phosphatase activity GO:0004722 TAS     protein kinase B binding GO:0043422 IPI     ion channel binding GO:0044325 IPI     protein C-terminus binding GO:0008022 ISO Biological Process     negative regulation of protein phosphorylation GO:0001933 IMP     negative regulation of calcium ion transmembrane transporter activity GO:1901020 IMP     cellular response to glucose stimulus GO:0071333 IMP     cardiac ventricle development GO:0003231 IEP     negative regulation of epithelial to mesenchymal transition GO:0010719 ISO     regulation of protein autophosphorylation GO:0031952 IMP     negative regulation of transcription factor import into nucleus GO:0042992 IMP     cellular response to cytokine stimulus GO:0071345 IEP     cellular response to steroid hormone stimulus GO:0071383 IEP     protein heterotrimerization GO:0070208 IMP     positive regulation of protein serine/threonine kinase activity GO:0071902 ISO     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IMP     regulation of protein catabolic process GO:0042176 IMP     cellular response to calcium ion GO:0071277 IEP     positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 IMP     heart development GO:0007507 IEP     meiotic cell cycle GO:0051321 IEA     cellular response to ethanol GO:0071361 IEP     protein dephosphorylation GO:0006470 IDA     positive regulation of apoptotic process GO:0043065 IMP     mesoderm development GO:0007498 ISO     positive regulation of protein phosphatase type 2A activity GO:0034049 IMP     positive regulation of protein dephosphorylation GO:0035307 IDA     cellular response to insulin stimulus GO:0032869 IEP     regulation of receptor activity GO:0010469 IMP     regulation of protein phosphorylation GO:0001932 IMP     cellular response to follicle-stimulating hormone stimulus GO:0071372 IEP Subcellular Localization     plasma membrane GO:0005886 ISO     nucleus GO:0005634 IEA     extracellular exosome GO:0070062 ISO     spindle pole GO:0000922 IEA     chromosome, centromeric region GO:0000775 ISO     neuron projection GO:0043005 IDA     terminal bouton GO:0043195 IDA     postsynaptic density GO:0014069 IDA     cytosol GO:0005829 ISO     cytoplasm GO:0005737 ISO     protein phosphatase type 2A complex GO:0000159 ISO