Gene description for Sod1
Gene name	superoxide dismutase 1, soluble
Gene symbol	Sod1
Other names/aliases	CuZnSOD
Species	Rattus norvegicus
Database cross references - Sod1
ExoCarta	ExoCarta_24786
Entrez Gene	24786
UniProt	P07632
Sod1 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Urine	20535238

Gene ontology annotations for Sod1

Molecular Function     Rac GTPase binding GO:0048365 ISO     identical protein binding GO:0042802 ISO     zinc ion binding GO:0008270 ISS     protein phosphatase 2B binding GO:0030346 ISS     copper ion binding GO:0005507 TAS     superoxide dismutase activity GO:0004784 ISS     enzyme binding GO:0019899 IPI     chaperone binding GO:0051087 ISS Biological Process     removal of superoxide radicals GO:0019430 TAS     sensory perception of sound GO:0007605 ISS     response to reactive oxygen species GO:0000302 ISO     superoxide metabolic process GO:0006801 TAS     cellular response to cadmium ion GO:0071276 IEP     locomotory behavior GO:0007626 ISS     oxidation-reduction process GO:0055114 ISO     glutathione metabolic process GO:0006749 ISS     positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902177 ISO     response to antipsychotic drug GO:0097332 IEP     myeloid cell homeostasis GO:0002262 ISS     aging GO:0007568 ISO     cellular iron ion homeostasis GO:0006879 ISS     response to ethanol GO:0045471 ISS     double-strand break repair GO:0006302 ISS     response to axon injury GO:0048678 ISS     positive regulation of superoxide anion generation GO:0032930 ISO     retrograde axon cargo transport GO:0008090 ISO     transmission of nerve impulse GO:0019226 ISS     response to organic substance GO:0010033 ISS     cell aging GO:0007569 ISS     auditory receptor cell stereocilium organization GO:0060088 ISS     cellular response to potassium ion GO:0035865 IEP     cellular response to ATP GO:0071318 IEP     anterograde axon cargo transport GO:0008089 ISO     relaxation of vascular smooth muscle GO:0060087 ISS     hydrogen peroxide biosynthetic process GO:0050665 ISS     regulation of mitochondrial membrane potential GO:0051881 ISS     activation of MAPK activity GO:0000187 ISS     ovarian follicle development GO:0001541 ISS     response to superoxide GO:0000303 ISS     negative regulation of apoptotic process GO:0043066 ISO     heart contraction GO:0060047 ISS     regulation of multicellular organism growth GO:0040014 ISS     response to copper ion GO:0046688 IMP     response to nutrient levels GO:0031667 IEP     response to heat GO:0009408 ISS     peripheral nervous system myelin maintenance GO:0032287 ISS     spermatogenesis GO:0007283 ISS     regulation of GTPase activity GO:0043087 ISO     negative regulation of cholesterol biosynthetic process GO:0045541 ISS     regulation of protein kinase activity GO:0045859 ISS     response to amphetamine GO:0001975 IEP     cellular response to oxidative stress GO:0034599 IEP     response to drug GO:0042493 ISS     response to carbon monoxide GO:0034465 IEP     positive regulation of catalytic activity GO:0043085 ISS     retina homeostasis GO:0001895 ISS     superoxide anion generation GO:0042554 ISO     negative regulation of neuron apoptotic process GO:0043524 ISS     muscle cell cellular homeostasis GO:0046716 ISS     reactive oxygen species metabolic process GO:0072593 ISS     regulation of blood pressure GO:0008217 ISS     response to oxidative stress GO:0006979 TAS     embryo implantation GO:0007566 ISS     neurofilament cytoskeleton organization GO:0060052 ISS     response to antibiotic GO:0046677 IEP     positive regulation of cytokine production GO:0001819 ISS     apoptotic DNA fragmentation GO:0006309 ISS     response to hydrogen peroxide GO:0042542 ISS Subcellular Localization     peroxisome GO:0005777 ISO     plasma membrane GO:0005886 ISS     secretory granule GO:0030141 IDA     cytoplasm GO:0005737 ISS     dendrite cytoplasm GO:0032839 ISS     extracellular matrix GO:0031012 ISS     protein complex GO:0043234 ISS     extracellular region GO:0005576 IDA     cytosol GO:0005829 ISS     neuronal cell body GO:0043025 ISS     mitochondrial intermembrane space GO:0005758 IDA     extracellular exosome GO:0070062 ISO     neuron projection GO:0043005 IDA     nucleus GO:0005634 ISS     cell GO:0005623 ISO     intracellular GO:0005622 ISO     dense core granule GO:0031045 IDA     mitochondrion GO:0005739 ISS     lysosome GO:0005764 IDA     cytoplasmic vesicle GO:0031410 ISS     nucleoplasm GO:0005654 ISO     myelin sheath GO:0043209 ISO     extracellular space GO:0005615 ISS