Gene description for Dnm2
Gene name	dynamin 2
Gene symbol	Dnm2
Other names/aliases	DYIIAAB
Species	Rattus norvegicus
Database cross references - Dnm2
ExoCarta	ExoCarta_25751
Vesiclepedia	VP_25751
Entrez Gene	25751
UniProt	P39052
Dnm2 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Dnm2

Molecular Function     GTPase activity GO:0003924 TAS     protein kinase binding GO:0019901 IPI     protein complex binding GO:0032403 IDA     protein binding GO:0005515 IPI     D2 dopamine receptor binding GO:0031749 IPI     nitric-oxide synthase binding GO:0050998 IDA     WW domain binding GO:0050699 IPI     SH3 domain binding GO:0017124 ISO     GTP binding GO:0005525 TAS     phosphatidylinositol 3-kinase regulatory subunit binding GO:0036312 IDA Biological Process     G-protein coupled receptor internalization GO:0002031 IMP     positive regulation of endocytosis GO:0045807 IMP     regulation of axon extension GO:0030516 IMP     transferrin transport GO:0033572 ISO     response to cocaine GO:0042220 IEP     positive regulation of nitric oxide biosynthetic process GO:0045429 IMP     receptor internalization GO:0031623 ISO     positive regulation of phagocytosis GO:0050766 IMP     regulation of Golgi organization GO:1903358 IMP     cellular response to nitric oxide GO:0071732 IEP     cellular response to carbon monoxide GO:0071245 IEP     macropinocytosis GO:0044351 IMP     receptor-mediated endocytosis GO:0006898 IMP     cilium morphogenesis GO:0060271 IMP     endocytosis GO:0006897 TAS     positive regulation of lamellipodium assembly GO:0010592 IMP     positive regulation of substrate adhesion-dependent cell spreading GO:1900026 IMP     metabolic process GO:0008152 IEA     positive regulation of sodium:potassium-exchanging ATPase activity GO:1903408 IMP     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IMP     spermatogenesis GO:0007283 IEP     negative regulation of membrane tubulation GO:1903526 ISO     cellular response to dopamine GO:1903351 IDA     response to light stimulus GO:0009416 IEP     regulation of Rac protein signal transduction GO:0035020 IMP     cellular response to X-ray GO:0071481 IEP     Golgi to plasma membrane transport GO:0006893 IMP     neuron projection morphogenesis GO:0048812 IMP Subcellular Localization     focal adhesion GO:0005925 ISO     extracellular exosome GO:0070062 ISO     coated pit GO:0005905 IDA     trans-Golgi network GO:0005802 IDA     postsynaptic membrane GO:0045211 ISS     cell junction GO:0030054 IDA     Golgi membrane GO:0000139 IDA     centrosome GO:0005813 IDA     growth cone GO:0030426 IDA     microtubule GO:0005874 ISO     protein complex GO:0043234 IDA     postsynaptic density GO:0014069 IEA     cytoplasm GO:0005737 ISO     Golgi apparatus GO:0005794 ISO     lamellipodium GO:0030027 IDA     phagocytic cup GO:0001891 IDA     endosome GO:0005768 IDA     photoreceptor inner segment GO:0001917 ISO     nucleus GO:0005634 IDA     midbody GO:0030496 IEA     perinuclear region of cytoplasm GO:0048471 IDA     ruffle membrane GO:0032587 IDA     plasma membrane GO:0005886 TAS     cytosol GO:0005829 ISO     clathrin-coated endocytic vesicle GO:0045334 IDA