Gene description for PLEK2
Gene name pleckstrin 2
Gene symbol PLEK2
Other names/aliases -
Species Homo sapiens
 Database cross references - PLEK2
ExoCarta ExoCarta_26499
Entrez Gene 26499
HGNC 19238
MIM 608007
UniProt Q9NYT0  
 PLEK2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PLEK2
Biological Process
    actin cytoskeleton organization GO:0030036 TAS
    intracellular signal transduction GO:0035556 IEA
Subcellular Localization
    lamellipodium membrane GO:0031258 IEA
    cytoskeleton GO:0005856 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PLEK2 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PLEK2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PLEK2 is involved
No pathways found





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