Gene description for Ddx3y
Gene name DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
Gene symbol Ddx3y
Other names/aliases 8030469F12Rik
D1Pas1-rs1
Dby
Species Mus musculus
 Database cross references - Ddx3y
ExoCarta ExoCarta_26900
Vesiclepedia VP_26900
Entrez Gene 26900
UniProt Q62095  
 Ddx3y identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ddx3y
Molecular Function
    hydrolase activity GO:0016787 IEA
    ATP-dependent RNA helicase activity GO:0004004 IBA
    nucleic acid binding GO:0003676 IEA
    ATP binding GO:0005524 IEA
    helicase activity GO:0004386 IEA
    nucleotide binding GO:0000166 IEA
    RNA binding GO:0003723 IEA
Biological Process
    translational initiation GO:0006413 IBA
    regulation of gene expression GO:0010468 IBA
    chromosome segregation GO:0007059 IBA
    RNA secondary structure unwinding GO:0010501 IBA
Subcellular Localization
    cytoplasmic ribonucleoprotein granule GO:0036464 IBA
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IEA
    membrane GO:0016020 ISO
 Experiment description of studies that identified Ddx3y in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ddx3y
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ddx3y is involved
No pathways found





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