Gene description for AMY1B
Gene name amylase, alpha 1B (salivary)
Gene symbol AMY1B
Other names/aliases AMY1
Species Homo sapiens
 Database cross references - AMY1B
ExoCarta ExoCarta_277
Vesiclepedia VP_277
Entrez Gene 277
HGNC 475
MIM 104701
UniProt P04745  
 AMY1B identified in sEVs derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for AMY1B
Molecular Function
    alpha-amylase activity GO:0004556 IBA
    alpha-amylase activity GO:0004556 IDA
    calcium ion binding GO:0005509 IDA
    chloride ion binding GO:0031404 IDA
Biological Process
    carbohydrate metabolic process GO:0005975 IBA
    oligosaccharide metabolic process GO:0009311 IDA
Subcellular Localization
    extracellular space GO:0005615 HDA
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified AMY1B in sEVs
1
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for AMY1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RIT1 6016
Negative Genetic Homo sapiens
2 KRAS 3845
Negative Genetic Homo sapiens
View the network image/svg+xml
 Pathways in which AMY1B is involved
No pathways found





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