Gene description for ALB
Gene name albumin
Gene symbol ALB
Other names/aliases -
Species Bos taurus
 Database cross references - ALB
ExoCarta ExoCarta_280717
Entrez Gene 280717
UniProt P02769  
 ALB identified in exosomes derived from the following tissue/cell type
Milk 23459212    
Serum 19327352    
 Gene ontology annotations for ALB
Molecular Function
    drug binding GO:0008144 ISS
    chaperone binding GO:0051087 IEA
    toxic substance binding GO:0015643 ISS
    pyridoxal phosphate binding GO:0030170 ISS
    oxygen binding GO:0019825 ISS
    metal ion binding GO:0046872 IEA
    fatty acid binding GO:0005504 ISS
    DNA binding GO:0003677 ISS
Biological Process
    negative regulation of apoptotic process GO:0043066 ISS
    hemolysis by symbiont of host erythrocytes GO:0019836 ISS
    retina homeostasis GO:0001895 IEA
    maintenance of mitochondrion location GO:0051659 ISS
    transport GO:0006810 IEA
    cellular response to starvation GO:0009267 ISS
Subcellular Localization
    blood microparticle GO:0072562 IEA
    protein complex GO:0043234 ISS
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IEA
    nucleus GO:0005634 IEA
    extracellular region GO:0005576 TAS
 Experiment description of studies that identified ALB in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 187
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ALB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LRP2 4036
Reconstituted Complex Homo sapiens
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