Gene description for FN1
Gene name fibronectin 1
Gene symbol FN1
Other names/aliases FN
Species Bos taurus
 Database cross references - FN1
ExoCarta ExoCarta_280794
Entrez Gene 280794
 FN1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FN1
Molecular Function
    peptidase activator activity GO:0016504 ISS
    heparin binding GO:0008201 IEA
Biological Process
    cell adhesion GO:0007155 ISS
    regulation of cell shape GO:0008360 IEA
    angiogenesis GO:0001525 IEA
    acute-phase response GO:0006953 IEA
    wound healing GO:0042060 ISS
    cell-substrate junction assembly GO:0007044 ISS
    positive regulation of peptidase activity GO:0010952 ISS
    cell-matrix adhesion GO:0007160 ISS
Subcellular Localization
    apical plasma membrane GO:0016324 ISS
    extracellular region GO:0005576 TAS
    proteinaceous extracellular matrix GO:0005578 ISS
 Experiment description of studies that identified FN1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FN1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FN1 is involved
No pathways found





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