Gene description for GNB1
Gene name guanine nucleotide binding protein (G protein), beta polypeptide 1
Gene symbol GNB1
Other names/aliases -
Species Bos taurus
 Database cross references - GNB1
ExoCarta ExoCarta_281201
Entrez Gene 281201
UniProt P62871  
 GNB1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GNB1
Molecular Function
    protein binding GO:0005515 IPI
    GTPase binding GO:0051020 IEA
    signal transducer activity GO:0004871 IEA
    GTPase activity GO:0003924 IEA
    protein complex binding GO:0032403 IEA
Biological Process
    cellular response to catecholamine stimulus GO:0071870 IDA
    adenylate cyclase-activating dopamine receptor signaling pathway GO:0007191 IDA
    sensory perception of taste GO:0050909 IEA
    cellular response to prostaglandin E stimulus GO:0071380 IDA
    cell proliferation GO:0008283 IEA
    phospholipase C-activating G-protein coupled receptor signaling pathway GO:0007200 IEA
    retina development in camera-type eye GO:0060041 IEA
    metabolic process GO:0008152 IEA
Subcellular Localization
    intracellular GO:0005622 IDA
    membrane GO:0016020 IDA
    lysosomal membrane GO:0005765 IEA
    extracellular exosome GO:0070062 IEA
    heterotrimeric G-protein complex GO:0005834 IDA
    photoreceptor disc membrane GO:0097381 TAS
 Experiment description of studies that identified GNB1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GNB1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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