Gene description for Trpm2
Gene name	transient receptor potential cation channel, subfamily M, member 2
Gene symbol	Trpm2
Other names/aliases	9830168K16Rik C79133 LTRPC2 TRPC7 Trp7 Trrp7
Species	Mus musculus
Database cross references - Trpm2
ExoCarta	ExoCarta_28240
Vesiclepedia	VP_28240
Entrez Gene	28240
Trpm2 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Trpm2

Molecular Function     monoatomic cation channel activity GO:0005261 ISO     monoatomic cation channel activity GO:0005261 ISS     sodium channel activity GO:0005272 IEA     manganese ion transmembrane transporter activity GO:0005384 IDA     calcium ion binding GO:0005509 ISO     calcium ion binding GO:0005509 ISS     intracellularly gated calcium channel activity GO:0015278 ISO     intracellularly gated calcium channel activity GO:0015278 ISS     hydrolase activity GO:0016787 ISS     ADP-ribose diphosphatase activity GO:0047631 ISS     mono-ADP-D-ribose binding GO:0072571 ISO     mono-ADP-D-ribose binding GO:0072571 ISS     ligand-gated calcium channel activity GO:0099604 IBA     ligand-gated calcium channel activity GO:0099604 IMP     ligand-gated calcium channel activity GO:0099604 ISO     ligand-gated calcium channel activity GO:0099604 ISS Biological Process     temperature homeostasis GO:0001659 IMP     dendritic cell chemotaxis GO:0002407 IMP     manganese ion transport GO:0006828 IDA     response to heat GO:0009408 IMP     response to purine-containing compound GO:0014074 IEA     response to purine-containing compound GO:0014074 ISO     calcium-mediated signaling GO:0019722 IEA     positive regulation of insulin secretion GO:0032024 ISO     regulation of actin cytoskeleton organization GO:0032956 ISO     regulation of actin cytoskeleton organization GO:0032956 ISS     response to hydroperoxide GO:0033194 IDA     sodium ion transmembrane transport GO:0035725 IEA     release of sequestered calcium ion into cytosol GO:0051209 IBA     release of sequestered calcium ion into cytosol GO:0051209 IMP     release of sequestered calcium ion into cytosol GO:0051209 ISO     protein homotetramerization GO:0051289 ISO     protein homotetramerization GO:0051289 ISS     regulation of filopodium assembly GO:0051489 ISO     regulation of filopodium assembly GO:0051489 ISS     cellular response to hydrogen peroxide GO:0070301 ISO     cellular response to hydrogen peroxide GO:0070301 ISS     calcium ion transmembrane transport GO:0070588 ISO     calcium ion transmembrane transport GO:0070588 ISS     cellular response to calcium ion GO:0071277 ISO     cellular response to calcium ion GO:0071277 ISS     manganese ion transmembrane transport GO:0071421 IEA     cellular response to temperature stimulus GO:0071502 IMP     zinc ion transmembrane transport GO:0071577 ISO     zinc ion transmembrane transport GO:0071577 ISS     dendritic cell differentiation GO:0097028 IMP     calcium ion transmembrane import into cytosol GO:0097553 ISO     calcium ion transmembrane import into cytosol GO:0097553 ISS     calcium ion import across plasma membrane GO:0098703 IMP     calcium ion import across plasma membrane GO:0098703 ISO     positive regulation of cellular response to oxidative stress GO:1900409 ISO Subcellular Localization     lysosome GO:0005764 ISO     lysosomal membrane GO:0005765 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     cytoplasmic vesicle membrane GO:0030659 IDA     cell projection GO:0042995 IEA     neuronal cell body GO:0043025 ISO     perikaryon GO:0043204 IEA