Gene description for IGHV3-7
Gene name immunoglobulin heavy variable 3-7
Gene symbol IGHV3-7
Other names/aliases IGHV37
VH
Species Homo sapiens
 Database cross references - IGHV3-7
ExoCarta ExoCarta_28452
Vesiclepedia VP_28452
Entrez Gene 28452
HGNC 5620
 IGHV3-7 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for IGHV3-7
Molecular Function
    antigen binding GO:0003823 IBA
    antigen binding GO:0003823 NAS
Biological Process
    immune response GO:0006955 NAS
    immunoglobulin mediated immune response GO:0016064 IBA
Subcellular Localization
    extracellular region GO:0005576 NAS
    extracellular region GO:0005576 TAS
    plasma membrane GO:0005886 TAS
    immunoglobulin complex GO:0019814 IEA
    extracellular exosome GO:0070062 HDA
    blood microparticle GO:0072562 HDA
 Experiment description of studies that identified IGHV3-7 in sEVs
1
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for IGHV3-7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MYC  
Affinity Capture-MS Homo sapiens
2 SMURF1 57154
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which IGHV3-7 is involved
No pathways found





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