Gene description for Dcn
Gene name decorin
Gene symbol Dcn
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Dcn
ExoCarta ExoCarta_29139
Entrez Gene 29139
UniProt Q01129  
 Dcn identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Dcn
Molecular Function
    protein N-terminus binding GO:0047485 IDA
    glycosaminoglycan binding GO:0005539 ISO
    poly(A) RNA binding GO:0044822 ISO
    extracellular matrix binding GO:0050840 ISO
    collagen binding GO:0005518 IDA
Biological Process
    response to lipopolysaccharide GO:0032496 IEP
    kidney development GO:0001822 IEP
    aging GO:0007568 IEP
    wound healing GO:0042060 IEP
    placenta development GO:0001890 IEP
    peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan GO:0019800 ISO
    response to mechanical stimulus GO:0009612 IEP
    skeletal muscle tissue development GO:0007519 IEP
    positive regulation of autophagy GO:0010508 ISO
Subcellular Localization
    extracellular matrix GO:0031012 ISO
    proteinaceous extracellular matrix GO:0005578 IDA
    collagen type VI trimer GO:0005589 IDA
    extracellular space GO:0005615 ISO
 Experiment description of studies that identified Dcn in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Dcn
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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