Gene description for Otub1
Gene name	OTU deubiquitinase, ubiquitin aldehyde binding 1
Gene symbol	Otub1
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Otub1
ExoCarta	ExoCarta_293705
Vesiclepedia	VP_293705
Entrez Gene	293705
UniProt	B2RYG6
Otub1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Otub1

Molecular Function     cysteine-type deubiquitinase activity GO:0004843 IBA     cysteine-type deubiquitinase activity GO:0004843 IEA     cysteine-type deubiquitinase activity GO:0004843 ISO     cysteine-type deubiquitinase activity GO:0004843 ISS     cysteine-type peptidase activity GO:0008234 IEA     deNEDDylase activity GO:0019784 ISO     deNEDDylase activity GO:0019784 ISS     ubiquitin protein ligase binding GO:0031625 ISO     ubiquitin binding GO:0043130 IBA     ubiquitin binding GO:0043130 IEA     ubiquitin binding GO:0043130 ISO     ubiquitin binding GO:0043130 ISS     ubiquitin-protein transferase inhibitor activity GO:0055105 ISO     ubiquitin-protein transferase inhibitor activity GO:0055105 ISS Biological Process     adaptive immune response GO:0002250 IEA     DNA repair GO:0006281 IEA     proteolysis GO:0006508 IEA     DNA damage response GO:0006974 IBA     DNA damage response GO:0006974 ISO     DNA damage response GO:0006974 ISS     protein deubiquitination GO:0016579 IEA     protein deubiquitination GO:0016579 ISO     protein deubiquitination GO:0016579 ISS     protein K48-linked deubiquitination GO:0071108 ISO     protein K48-linked deubiquitination GO:0071108 ISS     cellular response to interleukin-1 GO:0071347 IEP     positive regulation of TORC1 signaling GO:1904263 ISO     positive regulation of TORC1 signaling GO:1904263 ISS     negative regulation of double-strand break repair GO:2000780 ISO     negative regulation of double-strand break repair GO:2000780 ISS Subcellular Localization     cytoplasm GO:0005737 IEA     membrane GO:0016020 IEA