Gene description for Capn2
Gene name calpain 2, (m/II) large subunit
Gene symbol Capn2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Capn2
ExoCarta ExoCarta_29154
Entrez Gene 29154
UniProt Q07009  
 Capn2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Capn2
Molecular Function
    protein heterodimerization activity GO:0046982 IPI
    cytoskeletal protein binding GO:0008092 IDA
    calcium ion binding GO:0005509 IDA
    calcium-dependent cysteine-type endopeptidase activity GO:0004198 ISO
    peptidase activity GO:0008233 ISO
    protein binding GO:0005515 IPI
Biological Process
    response to hypoxia GO:0001666 IEP
    proteolysis GO:0006508 TAS
    protein autoprocessing GO:0016540 IDA
    myoblast fusion GO:0007520 ISO
    regulation of cytoskeleton organization GO:0051493 IEA
    blastocyst development GO:0001824 ISO
    cellular response to amino acid stimulus GO:0071230 ISO
Subcellular Localization
    dendrite GO:0030425 IDA
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 TAS
    chromatin GO:0000785 ISO
    extracellular exosome GO:0070062 ISO
    focal adhesion GO:0005925 ISO
    pseudopodium GO:0031143 ISO
    membrane raft GO:0045121 ISS
    cytosol GO:0005829 ISS
    Golgi apparatus GO:0005794 ISO
    perinuclear endoplasmic reticulum GO:0097038 ISO
    endoplasmic reticulum GO:0005783 ISO
    lysosome GO:0005764 ISO
    plasma membrane GO:0005886 ISS
 Experiment description of studies that identified Capn2 in exosomes
Experiment ID 225
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Capn2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Capn2 is involved
No pathways found

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