Gene description for GRM7
Gene name	glutamate receptor, metabotropic 7
Gene symbol	GRM7
Other names/aliases	GLUR7 GPRC1G MGLU7 MGLUR7 PPP1R87
Species	Homo sapiens
Database cross references - GRM7
ExoCarta	ExoCarta_2917
Vesiclepedia	VP_2917
Entrez Gene	2917
HGNC	4599
MIM	604101
UniProt	Q14831
GRM7 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for GRM7

Molecular Function     group III metabotropic glutamate receptor activity GO:0001642 IBA     group III metabotropic glutamate receptor activity GO:0001642 IDA     calcium ion binding GO:0005509 IDA     glutamate receptor activity GO:0008066 IDA     adenylate cyclase inhibitor activity GO:0010855 IDA     glutamate binding GO:0016595 IDA     PDZ domain binding GO:0030165 NAS     protein dimerization activity GO:0046983 IMP     serine binding GO:0070905 IDA Biological Process     behavioral fear response GO:0001662 IMP     adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0007193 IDA     adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway GO:0007196 IDA     G protein-coupled glutamate receptor signaling pathway GO:0007216 IBA     chemical synaptic transmission GO:0007268 IDA     sensory perception of sound GO:0007605 IMP     negative regulation of glutamate secretion GO:0014050 ISS     regulation of synaptic transmission, glutamatergic GO:0051966 IBA     axon development GO:0061564 IMP     glycosylation GO:0070085 IDA Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IMP     plasma membrane GO:0005886 NAS     plasma membrane GO:0005886 TAS     cell cortex GO:0005938 IDA     membrane GO:0016020 IDA     axon GO:0030424 ISS     dendrite GO:0030425 IDA     asymmetric synapse GO:0032279 ISS     dendritic shaft GO:0043198 ISS     receptor complex GO:0043235 IDA     postsynaptic membrane GO:0045211 ISS     presynaptic active zone GO:0048786 ISS