Gene description for Psenen
Gene name	presenilin enhancer gamma secretase subunit
Gene symbol	Psenen
Other names/aliases	RGD1312037
Species	Rattus norvegicus
Database cross references - Psenen
ExoCarta	ExoCarta_292788
Vesiclepedia	VP_292788
Entrez Gene	292788
UniProt	Q6QI68
Psenen identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Psenen

Molecular Function     enzyme binding GO:0019899 ISO     endopeptidase activator activity GO:0061133 ISO Biological Process     membrane protein ectodomain proteolysis GO:0006509 ISO     Notch signaling pathway GO:0007219 IEA     Notch receptor processing GO:0007220 IBA     Notch receptor processing GO:0007220 ISO     positive regulation of endopeptidase activity GO:0010950 ISO     protein processing GO:0016485 ISO     membrane protein intracellular domain proteolysis GO:0031293 ISO     amyloid-beta formation GO:0034205 ISO     amyloid-beta formation GO:0034205 ISS     amyloid precursor protein metabolic process GO:0042982 ISO     amyloid precursor protein metabolic process GO:0042982 ISS     amyloid precursor protein catabolic process GO:0042987 ISO Subcellular Localization     endoplasmic reticulum GO:0005783 ISO     endoplasmic reticulum membrane GO:0005789 IEA     Golgi apparatus GO:0005794 ISO     plasma membrane GO:0005886 ISO     membrane GO:0016020 ISO     membrane GO:0016020 ISS     Golgi cisterna membrane GO:0032580 IEA     presynaptic membrane GO:0042734 IDA     gamma-secretase complex GO:0070765 IBA     gamma-secretase complex GO:0070765 ISO     gamma-secretase complex GO:0070765 ISS