Gene description for Krt1
Gene name keratin 1, type II
Gene symbol Krt1
Other names/aliases Kb1
Species Rattus norvegicus
 Database cross references - Krt1
ExoCarta ExoCarta_300250
Entrez Gene 300250
UniProt Q6IMF3  
 Krt1 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Krt1
Molecular Function
    structural molecule activity GO:0005198 IEA
    molecular_function GO:0003674 ND
    carbohydrate binding GO:0030246 ISO
Biological Process
    establishment of skin barrier GO:0061436 ISO
    biological_process GO:0008150 ND
    complement activation, lectin pathway GO:0001867 ISO
    retina homeostasis GO:0001895 ISO
    negative regulation of inflammatory response GO:0050728 ISO
Subcellular Localization
    cellular_component GO:0005575 ND
    membrane GO:0016020 ISO
    extracellular space GO:0005615 ISO
    blood microparticle GO:0072562 ISO
    extracellular exosome GO:0070062 ISO
    extracellular matrix GO:0031012 ISO
    plasma membrane GO:0005886 IEA
    nucleus GO:0005634 ISO
    keratin filament GO:0045095 ISO
 Experiment description of studies that identified Krt1 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Krt1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Krt1 is involved
No pathways found





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