Gene description for Rqcd1
Gene name Rcd1 required for cell differentiation1 homolog (S. pombe)
Gene symbol Rqcd1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Rqcd1
ExoCarta ExoCarta_301513
Entrez Gene 301513
UniProt Q5PQL2  
 Rqcd1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Rqcd1
Molecular Function
    protein binding GO:0005515 IPI
    protein domain specific binding GO:0019904 ISO
    protein homodimerization activity GO:0042803 ISO
Biological Process
    positive regulation of ligand-dependent nuclear receptor transcription coactivator activity GO:2000327 ISS
    negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 ISS
    regulation of transcription, DNA-templated GO:0006355 IEA
    regulation of translation GO:0006417 IEA
    transcription, DNA-templated GO:0006351 IEA
    cytokine-mediated signaling pathway GO:0019221 ISO
    gene silencing by RNA GO:0031047 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    CCR4-NOT complex GO:0030014 ISS
    cytoplasmic mRNA processing body GO:0000932 ISS
    membrane GO:0016020 ISO
 Experiment description of studies that identified Rqcd1 in exosomes
1
Experiment ID 90
ISEV standards
EM
EV Biophysical techniques
HSC70|HSP90|TSG101
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Rqcd1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rqcd1 is involved
No pathways found





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