Gene description for Yars
Gene name tyrosyl-tRNA synthetase
Gene symbol Yars
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Yars
ExoCarta ExoCarta_313047
Vesiclepedia VP_313047
Entrez Gene 313047
UniProt Q4KM49  
 Yars identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Yars
Molecular Function
    tRNA binding GO:0000049 IEA
    tyrosine-tRNA ligase activity GO:0004831 IBA
    tyrosine-tRNA ligase activity GO:0004831 IEA
    tyrosine-tRNA ligase activity GO:0004831 ISO
    tyrosine-tRNA ligase activity GO:0004831 ISS
    ATP binding GO:0005524 IEA
    small molecule binding GO:0036094 ISO
    small molecule binding GO:0036094 ISS
Biological Process
    tyrosyl-tRNA aminoacylation GO:0006437 IEA
    tyrosyl-tRNA aminoacylation GO:0006437 ISO
    response to starvation GO:0042594 IEA
    response to starvation GO:0042594 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    cytosol GO:0005829 ISO
    cytosol GO:0005829 ISS
    nuclear body GO:0016604 IEA
    nuclear body GO:0016604 ISO
 Experiment description of studies that identified Yars in exosomes
1
Experiment ID 95
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Yars
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Park7 117287
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Yars is involved
No pathways found





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