Gene ontology annotations for Hist1h4a |
|
Experiment description of studies that identified Hist1h4a in exosomes |
1 |
Experiment ID |
907 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
|
EV Enriched markers |
✔
HSPA5
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
37309723
|
Organism |
Mus musculus |
Experiment description |
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells |
Authors |
Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S. |
Journal name |
Proteomics
|
Publication year |
2023 |
Sample |
Colon cancer cells |
Sample name |
C26 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
2 |
Experiment ID |
303 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Cd63|Cd81|Cd9
|
EV Enriched markers |
✘
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
33431899
|
Organism |
Mus musculus |
Experiment description |
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance |
Authors |
Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG. |
Journal name |
Nat Commun
|
Publication year |
2021 |
Sample |
Faeces |
Sample name |
Intestinal epithelial cells - C57BL/6 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein Lipid miRNA |
Methods used in the study |
Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC |
|
|
3 |
Experiment ID |
304 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Cd63|Cd81|Cd9
|
EV Enriched markers |
✘
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
33431899
|
Organism |
Mus musculus |
Experiment description |
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance |
Authors |
Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG. |
Journal name |
Nat Commun
|
Publication year |
2021 |
Sample |
Faeces |
Sample name |
Intestinal epithelial cells - C57BL/6 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein Lipid miRNA |
Methods used in the study |
Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC |
|
|
4 |
Experiment ID |
210 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
CD81|FLOT1
|
EV Enriched markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23260141
|
Organism |
Mus musculus |
Experiment description |
Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. |
Authors |
Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL. |
Journal name |
Cell
|
Publication year |
2012 |
Sample |
Fibroblasts |
Sample name |
Normal-Fibroblasts (L cells) |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
5 |
Experiment ID |
15 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
CD63
|
EV Enriched markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
17486113
|
Organism |
Mus musculus Homo sapiens |
Experiment description |
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. |
Authors |
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO |
Journal name |
NCB
|
Publication year |
2007 |
Sample |
Mast cells |
Sample name |
MC9 Bone marrow-derived mast cells HMC-1 |
Isolation/purification methods |
Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.11-1.21 g/mL
|
Molecules identified in the study |
Protein mRNA miRNA |
Methods used in the study |
Mass spectrometry [MALDI TOF] Western blotting Microarray miRCURY LNA Array |
|
|
6 |
Experiment ID |
39 |
MISEV standards |
✔
IEM
|
EV Biophysical techniques |
✔
TSG101|HSC70|FLOT1
|
EV Enriched markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
15210972
|
Organism |
Mus musculus |
Experiment description |
Cells release prions in association with exosomes. |
Authors |
Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G |
Journal name |
PNAS
|
Publication year |
2004 |
Sample |
Mov neuroglial cells |
Sample name |
Mov neuroglial cell |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
1.14 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [QSTAR] Western blotting Immunoelectron Microscopy |
|
|
7 |
Experiment ID |
264 |
MISEV standards |
✘
|
EV Biophysical techniques |
✔
CD63|CD9
|
EV Enriched markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25242146
|
Organism |
Mus musculus |
Experiment description |
Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells |
Authors |
Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino |
Journal name |
Molecular Cell
|
Publication year |
2014 |
Sample |
Neural stem cells |
Sample name |
NPCs - Th2 treated |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.13-1.20 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
8 |
Experiment ID |
33 |
MISEV standards |
✔
EM|IEM
|
EV Biophysical techniques |
✔
Alix|TSG101
|
EV Enriched markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
21136642
|
Organism |
Mus musculus |
Experiment description |
Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? |
Authors |
Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J |
Journal name |
PROTEOMICS_CL
|
Publication year |
2007 |
Sample |
Oligodendrocytes |
Sample name |
Oligodendrocytes Oli-neu |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
1.10-1.14 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [QTOF] Western blotting Immunoelectron Microscopy |
|
|
9 |
Experiment ID |
908 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
|
EV Enriched markers |
✔
HSPA5
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
37309723
|
Organism |
Mus musculus |
Experiment description |
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells |
Authors |
Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S. |
Journal name |
Proteomics
|
Publication year |
2023 |
Sample |
T-cell lymphoma cells |
Sample name |
EL4 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
Protein-protein interactions for Hist1h4a |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
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Pathways in which Hist1h4a is involved |
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