Gene description for Pen
Gene name Pendulin
Gene symbol Pen
Other names/aliases 2.1
CG4799
DPend
Dalpha2
Dimp-alpha2
DmelCG4799
IMPalpha2
Imp-alpha2
Kap alpha2
Kap-alpha2
Kpna2
OHO31
Oho31
Rch1
alpha2
alpha2A-Kap
alphaKap2
anon-WO0140519.258
bs29g06.y1
imp alpha2
imp-alpha2
impalpha2
importin alpha2/pendulin
l(2)144/1
l(2)k14401
oho-31
oho31
pen
pen-2
Species Drosophila melanogaster
 Database cross references - Pen
ExoCarta ExoCarta_34338
Entrez Gene 34338
UniProt P52295  
 Pen identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Pen
 Experiment description of studies that identified Pen in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pen
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pen is involved
No pathways found





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