Gene description for EYS
Gene name eyes shut homolog (Drosophila)
Gene symbol EYS
Other names/aliases C6orf178
C6orf179
C6orf180
EGFL10
EGFL11
RP25
SPAM
bA166P24.2
bA307F22.3
bA74E24.1
dJ1018A4.2
dJ22I17.2
dJ303F19.1
Species Homo sapiens
 Database cross references - EYS
ExoCarta ExoCarta_346007
Vesiclepedia VP_346007
Entrez Gene 346007
HGNC 21555
MIM 612424
UniProt Q5T1H1  
 EYS identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for EYS
Molecular Function
    molecular_function GO:0003674 ND
    calcium ion binding GO:0005509 IEA
Biological Process
    detection of light stimulus involved in visual perception GO:0050908 IMP
    skeletal muscle tissue regeneration GO:0043403 IMP
Subcellular Localization
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified EYS in exosomes
1
Experiment ID 63
MISEV standards
EV Biophysical techniques
AQP2
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for EYS
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which EYS is involved
No pathways found





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