Gene description for CG6180
Gene name CG6180 gene product from transcript CG6180-RA
Gene symbol CG6180
Other names/aliases DmelCG6180
Species Drosophila melanogaster
 Database cross references - CG6180
ExoCarta ExoCarta_34683
Vesiclepedia VP_34683
Entrez Gene 34683
 CG6180 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for CG6180
Biological Process
    negative regulation of ERK1 and ERK2 cascade GO:0070373 ISS
Subcellular Localization
    cytosol GO:0005829 ISS
 Experiment description of studies that identified CG6180 in exosomes
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CG6180
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CG5104  
Two-hybrid Drosophila melanogaster
2 CG10026  
Two-hybrid Drosophila melanogaster
3 CG10237  
Two-hybrid Drosophila melanogaster
4 CG7924  
Affinity Capture-MS Drosophila melanogaster
5 fwe  
Two-hybrid Drosophila melanogaster
6 CG43386  
Two-hybrid Drosophila melanogaster
7 metl  
Two-hybrid Drosophila melanogaster
8 Uch 33397
Affinity Capture-MS Drosophila melanogaster
9 Tom20  
Proximity Label-MS Drosophila melanogaster
10 CG15211  
Two-hybrid Drosophila melanogaster
11 EndoB  
Two-hybrid Drosophila melanogaster
12 CG5703  
Two-hybrid Drosophila melanogaster
13 CG10672  
Affinity Capture-MS Drosophila melanogaster
14 CG12355  
Two-hybrid Drosophila melanogaster
15 CG9782  
Two-hybrid Drosophila melanogaster
16 CG43208  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml
 Pathways in which CG6180 is involved
No pathways found





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