Gene description for Got1
Gene name Glutamate oxaloacetate transaminase 1
Gene symbol Got1
Other names/aliases BEST:GH07823
CG8430
DmelCG8430
FBgn 1124
GOT-1
Got-1
Got2
Species Drosophila melanogaster
 Database cross references - Got1
ExoCarta ExoCarta_36782
Vesiclepedia VP_36782
Entrez Gene 36782
 Got1 identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Got1
Molecular Function
    L-aspartate:2-oxoglutarate aminotransferase activity GO:0004069 IDA
Biological Process
    2-oxoglutarate metabolic process GO:0006103 IDA
    aspartate catabolic process GO:0006533 IDA
    glutamate biosynthetic process GO:0006537 IDA
Subcellular Localization
    peroxisome GO:0005777 ISM
    cytosol GO:0005829 HDA
 Experiment description of studies that identified Got1 in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Got1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CG1129  
Affinity Capture-MS Drosophila melanogaster
2 Treh  
Affinity Capture-MS Drosophila melanogaster
3 RpS21  
Affinity Capture-MS Drosophila melanogaster
4 CG11777  
Affinity Capture-MS Drosophila melanogaster
5 CG18787  
Affinity Capture-MS Drosophila melanogaster
6 BthD  
Affinity Capture-MS Drosophila melanogaster
7 sty  
Two-hybrid Drosophila melanogaster
8 CG18789  
Affinity Capture-MS Drosophila melanogaster
9 Tom20  
Proximity Label-MS Drosophila melanogaster
10 CG14894  
Proximity Label-MS Drosophila melanogaster
11 Art8  
Affinity Capture-MS Drosophila melanogaster
12 CG1532  
Affinity Capture-MS Drosophila melanogaster
13 Sod 39251
Affinity Capture-MS Drosophila melanogaster
14 alpha-Est2  
Affinity Capture-MS Drosophila melanogaster
15 Rae1  
Affinity Capture-MS Drosophila melanogaster
16 Wdr82  
Affinity Capture-MS Drosophila melanogaster
17 CG1218  
Affinity Capture-MS Drosophila melanogaster
18 CG7492  
Affinity Capture-MS Drosophila melanogaster
19 Ccs  
Affinity Capture-MS Drosophila melanogaster
20 CG7049  
Affinity Capture-MS Drosophila melanogaster
21 Trx-2  
Affinity Capture-MS Drosophila melanogaster
22 Arc1  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which Got1 is involved
No pathways found





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