Gene description for Got1
Gene name Glutamate oxaloacetate transaminase 1
Gene symbol Got1
Other names/aliases BEST:GH07823
CG8430
DmelCG8430
FBgn 1124
GOT-1
Got-1
Got2
Species Drosophila melanogaster
 Database cross references - Got1
ExoCarta ExoCarta_36782
Entrez Gene 36782
 Got1 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Got1
Molecular Function
    L-aspartate:2-oxoglutarate aminotransferase activity GO:0004069 ISS
    pyridoxal phosphate binding GO:0030170 IEA
Biological Process
    glutamate biosynthetic process GO:0006537 IDA
    aspartate metabolic process GO:0006531 ISS
    imaginal disc-derived wing morphogenesis GO:0007476 IMP
Subcellular Localization
    peroxisome GO:0005777 ISM
    mitochondrial matrix GO:0005759 ISS
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Got1 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Got1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Got1 is involved
No pathways found





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