Gene description for Sod
Gene name Superoxide dismutase
Gene symbol Sod
Other names/aliases CG11793
Cu
Cu-Zn SOD
Cu/Zn SOD
Cu/Zn sod
Cu/Zn superoxide dismutase
Cu/ZnSOD
CuSOD
CuZn SOD
CuZn-SOD
CuZn-SOD1
CuZnSOD
Cu[2+]/Zn[2+]SOD
DmelCG11793
G
Mn SOD
SOD
SOD-1
SOD1
SODC_DROME
Sod-1
Sod1
To
To-1
Zn SOD
Zn Sod
Zn-SOD
ZnSod
cSOD
cSod
dSOD1
l(3)108
l(3)68Af'
l(3)G
sod
sod1
Species Drosophila melanogaster
 Database cross references - Sod
ExoCarta ExoCarta_39251
Entrez Gene 39251
UniProt P61851  
 Sod identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Sod
Molecular Function
    superoxide dismutase activity GO:0004784 NAS
    zinc ion binding GO:0008270 IBA
    antioxidant activity GO:0016209 NAS
    copper ion binding GO:0005507 IBA
    protein homodimerization activity GO:0042803 IPI
Biological Process
    age-dependent response to oxidative stress GO:0001306 IMP
    response to oxidative stress GO:0006979 IMP
    oxidation-reduction process GO:0055114 IEA
    regulation of mitochondrion degradation GO:1903146 IGI
    removal of superoxide radicals GO:0019430 NAS
    regulation of terminal button organization GO:2000331 IMP
    superoxide metabolic process GO:0006801 NAS
    determination of adult lifespan GO:0008340 TAS
    aging GO:0007568 TAS
Subcellular Localization
    mitochondrion GO:0005739 IBA
    cytosol GO:0005829 IBA
    cytoplasm GO:0005737 NAS
    peroxisome GO:0005777 ISS
    nucleus GO:0005634 IBA
 Experiment description of studies that identified Sod in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Sod
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sod is involved
No pathways found





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