Gene description for KCNH1
Gene name
potassium channel, voltage gated eag related subfamily H, member 1
Gene symbol
KCNH1
Other names/aliases
EAG EAG1 Kv10.1 TMBTS h-eag
Species
Homo sapiens
Database cross references - KCNH1
ExoCarta
ExoCarta_3756
Vesiclepedia
VP_3756
Entrez Gene
3756
HGNC
6250
MIM
603305
UniProt
O95259
KCNH1 identified in exosomes derived from the following tissue/cell type
Cholangiocarcinoma cells
31054213
Cholangiocarcinoma cells
31054213
Gene ontology annotations for KCNH1
Experiment description of studies that identified KCNH1 in exosomes
1
Experiment ID
1223
MISEV standards
✔
EM
EV Biophysical techniques
EV Enriched markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
31054213
Organism
Homo sapiens
Experiment description
Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors
Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C.
Journal name
Proteomics
Publication year
2019
Sample
Cholangiocarcinoma cells
Sample name
KKU-M213 - in-gel digestion
Isolation/purification methods
Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Sucrose density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
1224
MISEV standards
✔
EM
EV Biophysical techniques
EV Enriched markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
31054213
Organism
Homo sapiens
Experiment description
Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors
Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C.
Journal name
Proteomics
Publication year
2019
Sample
Cholangiocarcinoma cells
Sample name
KKU-M213D5 - in-gel digestion
Isolation/purification methods
Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Sucrose density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for KCNH1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
KCNF1
Two-hybrid
Homo sapiens
2
KCNC1
Two-hybrid
Homo sapiens
3
ALG10
Invitro
Homo sapiens
4
KCNB1
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
View the network
image/svg+xml
Pathways in which KCNH1 is involved