Gene description for ARMS2
Gene name age-related maculopathy susceptibility 2
Gene symbol ARMS2
Other names/aliases ARMD8
Species Homo sapiens
 Database cross references - ARMS2
ExoCarta ExoCarta_387715
Vesiclepedia VP_387715
Entrez Gene 387715
HGNC 32685
MIM 611313
UniProt P0C7Q2  
 ARMS2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for ARMS2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    retina homeostasis GO:0001895 IMP
Subcellular Localization
    photoreceptor inner segment GO:0001917 IDA
    mitochondrion GO:0005739 IDA
 Experiment description of studies that identified ARMS2 in exosomes
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for ARMS2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 OGDHL  
Affinity Capture-MS Homo sapiens
2 EEF1A2 1917
Affinity Capture-MS Homo sapiens
3 EFR3A 23167
Affinity Capture-MS Homo sapiens
4 ANXA13 312
Affinity Capture-MS Homo sapiens
5 MICAL1 64780
Affinity Capture-MS Homo sapiens
6 PRKCA 5578
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ARMS2 is involved
No pathways found





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