Gene description for YPEL2
Gene name yippee-like 2 (Drosophila)
Gene symbol YPEL2
Other names/aliases FKSG4
Species Homo sapiens
 Database cross references - YPEL2
ExoCarta ExoCarta_388403
Vesiclepedia VP_388403
Entrez Gene 388403
HGNC 18326
MIM 609723
UniProt Q96QA6  
 YPEL2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for YPEL2
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Subcellular Localization
    nucleolus GO:0005730 IEA
 Experiment description of studies that identified YPEL2 in exosomes
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for YPEL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SH2D4A 63898
Two-hybrid Homo sapiens
2 SRPK1 6732
Biochemical Activity Homo sapiens
3 SRPK2 6733
Biochemical Activity Homo sapiens
View the network image/svg+xml
 Pathways in which YPEL2 is involved
No pathways found





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