Gene description for DYTN
Gene name dystrotelin
Gene symbol DYTN
Other names/aliases -
Species Homo sapiens
 Database cross references - DYTN
ExoCarta ExoCarta_391475
Vesiclepedia VP_391475
Entrez Gene 391475
HGNC 23279
UniProt A2CJ06  
 DYTN identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for DYTN
Molecular Function
    zinc ion binding GO:0008270 IEA
Biological Process
    synaptic signaling GO:0099536 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    synapse GO:0045202 IEA
 Experiment description of studies that identified DYTN in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for DYTN
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TP53 7157
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which DYTN is involved
No pathways found





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