Gene description for AGO2
Gene name	Argonaute 2
Gene symbol	AGO2
Other names/aliases	AG02 AGO 2 Ago-2 Ago2 CG13452 CG7439 Dm Ago2 DmAgo2 DmelCG7439 ago ago-2 ago2 dAGO2 dAgo2 eIF2C2
Species	Drosophila melanogaster
Database cross references - AGO2
ExoCarta	ExoCarta_39683
Vesiclepedia	VP_39683
Entrez Gene	39683
UniProt	Q9VUQ5
AGO2 identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells	23035643

Gene ontology annotations for AGO2

Molecular Function     single-stranded RNA binding GO:0003727 IDA     RNA endonuclease activity GO:0004521 IDA     protein binding GO:0005515 IPI     RNA endonuclease activity, producing 5'-phosphomonoesters GO:0016891 IDA     siRNA binding GO:0035197 IDA     endoribonuclease activity, cleaving siRNA-paired mRNA GO:0070551 IDA Biological Process     pole cell formation GO:0007279 IMP     cellularization GO:0007349 IMP     segment polarity determination GO:0007367 IGI     dosage compensation by hyperactivation of X chromosome GO:0009047 IGI     RNAi-mediated antiviral immune response GO:0009616 IMP     siRNA processing GO:0030422 IDA     siRNA processing GO:0030422 IMP     piRNA processing GO:0034587 IMP     syncytial nuclear migration GO:0035190 IMP     regulatory ncRNA-mediated post-transcriptional gene silencing GO:0035194 IDA     regulatory ncRNA-mediated post-transcriptional gene silencing GO:0035194 IMP     miRNA-mediated post-transcriptional gene silencing GO:0035195 IMP     miRNA-mediated post-transcriptional gene silencing GO:0035195 IMP     negative regulation of viral genome replication GO:0045071 IMP     RNAi-mediated antiviral immunity against RNA virus GO:0051214 IMP     defense response to virus GO:0051607 IGI     defense response to virus GO:0051607 IMP     RISC complex assembly GO:0070922 IDA     RISC complex assembly GO:0070922 IMP     siRNA-mediated gene silencing by mRNA destabilization GO:0090625 IDA     siRNA-mediated gene silencing by mRNA destabilization GO:0090625 IMP     cellular response to virus GO:0098586 IMP     siRNA-mediated pericentric heterochromatin formation GO:0140727 IMP     piRNA-mediated gene silencing by mRNA destabilization GO:0140991 IMP     siRNA-mediated heterochromatin formation GO:0141194 IGI Subcellular Localization     nucleus GO:0005634 IDA     cytoplasm GO:0005737 IDA     cytosol GO:0005829 HDA     RISC complex GO:0016442 IDA     RISC complex GO:0016442 TAS     RISC-loading complex GO:0070578 IDA     RISC-loading complex GO:0070578 IGI     neuronal ribonucleoprotein granule GO:0071598 IDA