Gene description for LOC440434
Gene name
aminopeptidase puromycin sensitive pseudogene
Gene symbol
LOC440434
Other names/aliases
-
Species
Homo sapiens
Database cross references - LOC440434
ExoCarta
ExoCarta_440434
Vesiclepedia
VP_440434
Entrez Gene
440434
LOC440434 identified in sEVs derived from the following tissue/cell type
Retinal pigment epithelial cells
35333565
Retinal pigment epithelial cells
35333565
Gene ontology annotations for LOC440434
Experiment description of studies that identified LOC440434 in sEVs
1
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for LOC440434
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PFN1
5216
Co-fractionation
Homo sapiens
2
SERBP1
26135
Affinity Capture-MS
Homo sapiens
3
NFKBIE
Co-fractionation
Homo sapiens
4
PLEKHA4
57664
Affinity Capture-MS
Homo sapiens
5
LOC100132735
Protein-RNA
Homo sapiens
6
PRDX1
5052
Co-fractionation
Homo sapiens
7
SORD
6652
Co-fractionation
Homo sapiens
View the network
image/svg+xml
Pathways in which LOC440434 is involved
No pathways found