Gene description for Sec13
Gene name Sec13 ortholog (S. cerevisiae)
Gene symbol Sec13
Other names/aliases BEST:CK00043
BcDNA:LD03471
CG6773
CK00043
DmelCG6773
Dsec13
SEC13
l(3)01031
sec13
Species Drosophila melanogaster
 Database cross references - Sec13
ExoCarta ExoCarta_44437
Entrez Gene 44437
 Sec13 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Sec13
Molecular Function
    structural molecule activity GO:0005198 ISS
Biological Process
    SMAD protein import into nucleus GO:0007184 IMP
    larval chitin-based cuticle development GO:0008363 IMP
    negative regulation of gene expression GO:0010629 IDA
    NLS-bearing protein import into nucleus GO:0006607 IMP
    chitin-based larval cuticle pattern formation GO:0035293 IMP
    COPII-coated vesicle budding GO:0090114 ISS
    membrane budding GO:0006900 ISS
Subcellular Localization
    COPII vesicle coat GO:0030127 ISS
    nuclear pore outer ring GO:0031080 ISS
    Seh1-associated complex GO:0035859 ISS
 Experiment description of studies that identified Sec13 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Sec13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sec13 is involved
No pathways found





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