Gene description for Vha36-1
Gene name Vacuolar H[+] ATPase 36kD subunit 1
Gene symbol Vha36-1
Other names/aliases ATP6V1D
CG8186
DmelCG8186
Vha36
VhaD
anon-WO0153538.20
anon-WO0153538.21
anon-WO0153538.28
anon-WO02059370.27
l(2)k07207
vha36
vha36-1
Species Drosophila melanogaster
 Database cross references - Vha36-1
ExoCarta ExoCarta_44702
Entrez Gene 44702
UniProt Q9V7D2  
 Vha36-1 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Vha36-1
Molecular Function
    ATPase activity, coupled to transmembrane movement of substances GO:0042626 IEA
    proton-transporting ATPase activity, rotational mechanism GO:0046961 IC
Biological Process
    ATP hydrolysis coupled proton transport GO:0015991 IC
    proton transport GO:0015992 ISS
Subcellular Localization
    plasma membrane proton-transporting V-type ATPase complex GO:0033181 IMP
    vacuolar proton-transporting V-type ATPase, V1 domain GO:0000221 NAS
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified Vha36-1 in exosomes
1
Experiment ID 202
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG10|RAB35
EV Cytosolic markers
✔
FLOT2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Vha36-1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vha36-1 is involved
PathwayEvidenceSource
Insulin receptor recycling IEA Reactome
Transferrin endocytosis and recycling IEA Reactome





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