Gene description for Aats-ile
Gene name Isoleucyl-tRNA synthetase
Gene symbol Aats-ile
Other names/aliases CG11471
DmelCG11471
IRS
IleRS
l(3)00827
Species Drosophila melanogaster
 Database cross references - Aats-ile
ExoCarta ExoCarta_45785
Entrez Gene 45785
 Aats-ile identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Aats-ile
Molecular Function
    aminoacyl-tRNA editing activity GO:0002161 IEA
    ATP binding GO:0005524 IEA
    isoleucine-tRNA ligase activity GO:0004822 ISS
Biological Process
    isoleucyl-tRNA aminoacylation GO:0006428 ISS
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Aats-ile in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Aats-ile
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aats-ile is involved
No pathways found





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